Synthetic biology is an increasingly high‐profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA‐based device construction, genome‐driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into (...) two broader issues that define synthetic biology: the relationships between biology and engineering, and between synthesis and analysis. These themes also illuminate synthetic biology's connections to genetic and other forms of biological engineering, as well as to systems biology. We suggest that all these knowledge‐making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems. BioEssays 30:57–65, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

We use joint probabilities to analyze the EPR argument in the Bohm's example of spins.(1) The properties of distribution functions for two, three, or more noncommuting spin components are explicitly studied and their limitations are pointed out. Within the statistical ensemble interpretation of quantum theory (where only statements about repeated events can be made), the incompleteness of quantum theory does not follow, as the consistent use of joint probabilities shows. This does not exclude a completion of quantum mechanics, going beyond (...) it, by a more general theory of single events, using hidden variables, for example. (shrink)

Recent assertions that the present particle physics is on the path of a “final theory” which cannot be reduced to more fundamental ones is critically examined and confronted with a counter-thesis.

Pauli's five-dimensional Dirac equation in projective space, which results in an anomalous magnetic moment term in four dimensions, is related to the Schuster-Blackett law of the magnetic field of rotating bodies and to the recent results on the gyromagnetic ratio in Kaluza-Klein theories.

Vagueness in law leads to indeterminacies in legal rights and obligations in many cases. The book defends that claim and explains its implications for legal theory. Vague language is the book's focus, but vagueness is not merely a linguistic feature of law. Law is necessarily vague. That fact seems to threaten the coherence of the ideal of the rule of law. The book defends a new, coherent articulation of that ideal.

Looks into evaluation of information provision probability from different sources, based on use of linguistic variables. Formation of functions appurtenant for its unclear variables provides for adoption of decisions by the decision maker, in conditions of nonprobabilistic equivocation. The development of market relations in Ukraine increases the independence and responsibility of enterprises in justifying and making management decisions that ensure their effective, competitive activities. As a result of the analysis, it is determined that the condition of economic facilities can be (...) described and determined by the decision-maker, in the presence of the necessary information. The confidence of the decision-maker in the information received is different and the decisions made have a correspondingly different level of information risk. It is important to substantiate the procedure for assessing the numerical extent of information risk in decision-making based on the information obtained in conditions of uncertainty. The use of a linguistic variable in the processing of expert data presented in the form of a matrix of binary relations of values of the membership function, which allowed to move to further processing of knowledge to support decision-making in the management of industrial, commercial, financial and other activities. As a mathematical model for estimating the numerical measure of information risk when making decisions based on the information obtained in conditions of non-stochastic uncertainty, a model has been developed to model natural language uncertainties, which differs from existing ones by formalizing knowledge taking into account uncertainty of input information. Making such a clear decision in a fuzzy environment has appropriate values of effectiveness and risk. The paper proposes all the functions and accessories of indicators of both quantitative nature and qualitative nature to bring their values in the field of definition to one scale. Then the indicator of the effectiveness of decision-making will be a measure of the clarity of the cross-section of fuzzy subsets, which correspond to the introduced indicators of information risk. The condition of economic facilities can be described and determined by the decision-maker, if the necessary information is available. Decision-making on thenumerical measure of information risk must be determined by a set of basic indicators, which can be both quantitative and qualitative in nature. Predictive values of indicators should be determined in conditions of nonstochastic uncertainty. In this case, the indicators of a quantitative nature can be determined by fuzzy triangular numbers, which implement a high level of confidence in the subjective judgments of experts. Indicators of qualitative nature should be presented in linguistic variables. The values of the indicators of qualitative nature that are predicted must be considered for all fuzzy variable terms-sets of linguistic variables introduced into consideration. For any fuzzy variable, the introduction to the consideration of a clear set of values as carriers of the α-level of its membership function allows to reduce to a single interpretation of the predicted values of indicators of quantitative and qualitative nature in terms of non-stochastic uncertainty. (shrink)

Diese Arbeit zeigt, dass die Dualität des mathematischen und dynamischen Erhabenen bei Kant auch dem Zweck der dritten Kritik dient, die Kluft zwischen den Gebieten der Natur und der Freiheit zu schließen. In der Sekundärliteratur zu Kant wird das Erhabene oft als Anhang des Schönen oder aufgrund seiner mehrfachen Dualitäten als Bruch in Kants Ansatz angesehen. Dies geschieht, weil solche Interpretationen die Elemente der Theorie des Erhabenen atomisch und nicht systematisch rekonstruieren. Im Gegensatz dazu wird in dieser Arbeit mittels der (...) Resonanz der teleologischen Behandlung der Vernunft nicht nur die innere Systematik der dritten Kritik gezeigt, sondern auch die von der gesamten kritischen Philosophie. Die Vernunft als Vermögen der Zwecksetzung zu verstehen in ihrem praktischen und theoretischen Gebrauch, ist keine neue Idee oder neuer systematischer Rekonstruktionsversuch der kritischen Philosophie in der Kantforschung. Das eigentlich Neue in dieser Monografie ist, einen Beweis von ihrer teleologischen Einheit aus der ästhetischen Perspektive des paradoxen Gefühls des Erhabenen geleistet zu haben. (shrink)

Open peer commentary on the article “Designing Academic Conferences in the Light of Second-Order Cybernetics” by Laurence D. Richards. Upshot: I propose that a lack of a common ground or culture of understanding is a design flaw in academic conferences that creates opportunities for violent reactions. I suggest that an additional or revised design principle or praxis should be considered through application of second-order cybernetics.

Localised configurations of the free electromagnetic field are constructed, possessing properties of massive, spinning, relativistic particles. In an inertial frame, each configuration travels in a straight line at constant speed, less than the speed of lightc, while slowly spreading. It eventually decays into pulses of radiation travelling at speedc. Each configuration has a definite rest mass and internal angular momentum, or spin. Each can be of “electric” or “magnetic” type, according as the radial component of the magnetic or electric field (...) vanishes in the rest frame, and each has an “antiparticle.” Any such configuration, of electric or magnetic type, is characterized in part by a set of labels (κ, ω0, σ,l, m), where ω0 is the mean of the angular frequencies of the plane waves making up the configuration, σ is the variance of those frequencies, κ is a positive constant with dimensions of action, andl, m are angular momentum “quantum numbers” withl a positive integer andm an integer such that ‖m‖≤l. The rest energy of the “particle” is κω0, its spin is κ ‖m‖, and its lifetime is of the order of 1/σ. Its antiparticle has ω0 replaced by −ω0. (shrink)

The study investigated the influence of campus environmental factors on job commitments. The research design was quantitative descriptive sample survey of ex-post facto type while the population includes both male and female senior non-teaching staff of Olabisi Onabanjo University, Ogun State. Multi-stage sampling technique was used in choosing 200 participants selected from nine faculties and one college. A structured and close-ended questionnaire titled ‘Campus Environmental Factors and Job Commitment Questionnaire’ with reliability co-efficient of 0.85 obtained through Cronbach alpha methods was (...) administered. 170 were retrieved from the 200 instruments administered. Data were analysed using frequency count, simple percentage, Pearson Correlation, and t test of significance. The study demonstrated a significant positive influence of campus environmental factors on job commitments of staff in the university. Useful recommendations were also raised. (shrink)

The single postulate of Coulomb-Clausius potential between charges allows one to derive all of Maxwell's equations with an explicit form for polarizability.

QED is a fundamental microscopic theory satisfying all the conservation laws and discrete symmetries C, P, T. Yet, dissipative phenomena, organization, and self-organization occur even at this basic microscopic two-body level. How these processes come about and how they are described in QED is discussed. A possible new phase of QED due to self-energy effects leading to self-organization is predicted.

This is the first in a series of papers in which a method of harmonic analysis in terms of functions over the groupSU(2) is applied to the description of interaction between matter and the electromagnetic field. Carmeli'sSU(2) formulation of Maxwell's equations is extended to anSU(2) formulation of the equations for the electromagnetic vector potential. The four functions which describe the vector potential are expanded in a generalized Fourier series [SU(2) harmonic analysis] and the equations for the coefficients are derived. These (...) equations are not independent of each other, but in a given order they can be solved consecutively one at a time. (shrink)

v. 1 Na antiguidade e na Idade Média.--v. 2. A civilização do homem-exterior.

The mathematical and physical aspects of the conformal symmetry of space-time and of physical laws are analyzed. In particular, the group classification of conformally flat space-times, the conformal compactifications of space-time, and the problem of imbedding of the flat space-time in global four-dimensional curved spaces with non-trivial topological and geometrical structure are discussed in detail. The wave equations on the compactified space-times are analyzed also, and the set of their elementary solutions constructed. Finally, the implications of global compactified space-times for (...) cosmology are discussed. It is argued that the recent discovery of periodic structure of matter distribution on large distances strongly suggests that the global cosmological space-time should be close. Next we analyze the inflation scalar field in the inflationary model of universe evolution considered on the spatially compact Robertson-Walker space-time. It is shown that the energy distribution in this model is periodic and the periods and density decrease with increasing distance, in striking agreement with experimental data. Our model of the universe also provides a definite predictions for the energy distribution, polar and azimuthal, considered as a function of angles θ and φ. These predictions should be tested with the new astronomical data. (shrink)

The “theorems” showing the impossibility of ascribing to individual quantum systems a definite value of a set of observables, not necessarily commuting,1–4 are based on the tacit assumption that eachindividual spin component has a discrete dichotomic value. We show explicitly that it is possible to introduce continuous hidden variables for individual spins which avoid these quantum paradoxes without changing any of the observed quantum mechanical results.

We show that it is possible to consider parity and time reversal, as basic geometric symmetry operations, as being absolutely conserved. The observations of symmetry-violating pseudoscalar quantities can be attributed to the fact that some particles, due to their internal structure, are not eigenstates of parity or CP, and there is no reason that they should be. In terms of a model it is shown how, in spite of this, pseudoscalar terms are small in strong interactions. The neutrino plays an (...) essential role in these considerations. (shrink)

The symplectic structures (brackets, Hamilton's equations, and Lagrange's equations) for the Dirac electron and its classical model have exactly the same form. We give explicitly the Poisson brackets in the dynamical variables (x μ,p μ,v μ,S μv). The only difference is in the normalization of the Dirac velocities γμγμ=4 which has significant consequences.

Exact wavelet solutions of the wave equation for accelerating potentials are found and applied to single individual events in Stern-Gerlach experiment.

When looking at a scene, observers feel that they see its entire structure in great detail and can immediately notice any changes in it. However, when brief blank fields are placed between alternating displays of an original and a modified scene, a striking failure of perception is induced: identification of changes becomes extremely difficult, even when changes are large and made repeatedly. Identification is much faster when a verbal cue is provided, showing that poor visibility is not the cause of (...) this difficulty. Identification is also faster for objects mentioned in brief verbal descriptions of the scene. These results support the idea that observers never form a complete, detailed representation of their surroundings. In addition, results also indicate that attention is required to perceive change, and that in the absence of localized motion signals it is guided on the basis of high-level interest. (shrink)

In a previous article by two of the present authors Carmeli's group-theoretic method for the formulation of wave equations was applied to the case of the electromagnetic field, and the equations for the vector potential were derived. In the present paper a quantization procedure for these equations is carried out in the Lorentz gauge. It involves two independent variables, corresponding to the number of degrees of freedom of the electromagnetic field in a Hilbert space with a positive-definite metric. Conserved quantities (...) are derived. (shrink)